Allergic Conjunctivitis
๐ธ Allergic Conjunctivitis
๐ Definition
Allergic conjunctivitis is inflammation of the conjunctiva caused by an allergic reaction to environmental allergens. It's a non-infectious, immune-mediated response, often affecting both eyes.
๐จ Causes / Triggers
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Pollen (grass, trees, weeds – seasonal)
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Dust mites
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Animal dander
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Mold
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Contact lenses or solutions
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Air pollutants, smoke
๐ง Pathophysiology (Quick!)
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Allergen exposure triggers IgE-mediated hypersensitivity
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Mast cells in the conjunctiva release histamine, prostaglandins, and other inflammatory mediators
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Leads to vasodilation, increased tear production, and itching
๐️ Symptoms
| Symptom | Notes |
|---|---|
| Itching | Main feature – often severe |
| Redness | Bilateral and diffuse |
| Tearing (epiphora) | Clear, watery discharge |
| Burning or gritty feeling | Not painful, but irritating |
| Swollen eyelids | Due to inflammation |
| Photophobia | Mild, in some cases |
| Ropy, white mucous discharge | Especially in vernal keratoconjunctivitis |
๐ Signs on Examination
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Bilateral conjunctival injection (red eyes)
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Chemosis (conjunctival swelling)
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Papillae on the upper tarsal conjunctiva (especially in vernal type)
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Lid edema
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No preauricular lymphadenopathy (helps differentiate from viral)
๐ Types of Allergic Conjunctivitis
| Type | Description |
|---|---|
| Seasonal Allergic Conjunctivitis (SAC) | Most common – flares in spring/summer |
| Perennial Allergic Conjunctivitis (PAC) | Year-round – often from dust, pets |
| Vernal Keratoconjunctivitis (VKC) | Severe, often in boys, springtime, thick discharge |
| Atopic Keratoconjunctivitis (AKC) | Severe chronic form, often in adults with eczema |
๐ Treatment
| Approach | Details |
|---|---|
| Avoid allergens | Air purifiers, keep windows closed, no pets in bedroom |
| Cold compresses | Reduces itching and swelling |
| Artificial tears | Wash out allergens + soothe |
| Topical antihistamines | e.g. Olopatadine, Ketotifen |
| Mast cell stabilizers | e.g. Cromolyn sodium (takes days to work) |
| Dual-action drops | Antihistamine + mast cell stabilizer |
| Oral antihistamines | For systemic allergy control |
| Steroid eye drops | Short-term only, under supervision (risk of ↑ IOP, cataract) |
| Immunomodulators (e.g., cyclosporine) | In chronic or severe cases like VKC/AKC |
๐ง Key Clinical Pearls
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ITCHING = ALLERGIES until proven otherwise
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Typically bilateral
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No purulent discharge (differentiates from bacterial)
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Improves with antihistamines, worsens in allergy seasons
๐ When to Refer to Ophthalmology
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No response to treatment
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Severe symptoms (e.g., corneal involvement in VKC/AKC)
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Vision changes
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Frequent recurrences
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Steroid-dependent cases
๐งผ Prevention Tips
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Shower after being outdoors
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Change clothes and bedding frequently
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Keep pets out of sleeping areas
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Wear sunglasses to block pollen
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Avoid rubbing eyes (can worsen symptoms)
๐ฏ Summary Table
| Feature | Allergic Conjunctivitis |
|---|---|
| Cause | Environmental allergens |
| Discharge | Watery or ropy, not purulent |
| Laterality | Usually bilateral |
| Main symptom | Itching |
| Contagious? | ❌ No |
| Best treatment | Antihistamine + mast cell stabilizer drops |
| Steroid use | Short-term only under supervision |

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